Molecular Imaging in Atherosclerosis, Thrombosis, and Vascular Inflammation
نویسندگان
چکیده
منابع مشابه
Molecular imaging in atherosclerosis, thrombosis, and vascular inflammation.
Appreciation of the molecular and cellular processes of atherosclerosis, thrombosis, and vascular inflammation has identified new targets for imaging. The common goals of molecular imaging approaches are to accelerate and refine diagnosis, provide insights that reveal disease diversity, guide specific therapies, and monitor the effects of those therapies. Here we undertake a comparative analysi...
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Acute rupture of vulnerable plaques frequently leads to myocardial infarction and stroke. Within the last decades, several cellular and molecular players have been identified that promote atherosclerotic lesion formation, maturation and plaque rupture. It is now widely recognized that inflammation of the vessel wall and distinct leukocyte subsets are involved throughout all phases of atheroscle...
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Beat A. Kaufmann, John M. Sanders, Christopher Davis, Aris Xie, Patrick Aldred, Ian J. Detection of Vascular Cell Adhesion Molecule-1 Molecular Imaging of Inflammation in Atherosclerosis With Targeted Ultrasound Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2007 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Aven...
متن کاملMolecular imaging of inflammation in atherosclerosis with targeted ultrasound detection of vascular cell adhesion molecule-1.
BACKGROUND The ability to image vascular inflammatory responses may allow early diagnosis and treatment of atherosclerosis. We hypothesized that molecular imaging of vascular cell adhesion molecule-1 (VCAM-1) expression with contrast-enhanced ultrasound (CEU) could be used for this purpose. METHODS AND RESULTS Attachment of VCAM-1-targeted and control microbubbles to cultured endothelial cell...
متن کاملInflammation imaging in atherosclerosis.
Inflammation is important at many stages of atherosclerotic plaque development. We highlight several imaging modalities that can quantify the degree of plaque inflammation noninvasively. Imaging of this type might allow testing of novel antiatherosclerosis drugs, identification of patients at risk of plaque rupture, and deeper insight into the biology of the disease. The imaging modalities are ...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2009
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.108.165498